Microneedle Mesotherapy – Dermapen 4.0 is a treatment designed to reduce wrinkles, stretch marks, and scars by stimulating the skin’s natural regeneration processes. Dermapen 4.0 uses a system of pulsating needles that gently puncture the skin, triggering the production of collagen and elastin. This leads to tissue remodeling and structural renewal.
As a result, blood circulation improves, and the skin becomes firmer and more resilient due to the formation of new collagen. The treatment offers relatively fast and long-lasting results, making it a strong alternative to other therapies.
Treatment Area Map

A – Face
B – Neck
C – Décolletage
1 area = A
2 areas = A + B , or A + C , or B + C
3 areas = A + B + C
Perceptibility
Duration
60 min
Recovery time
3 days
Number of treatments in a series
3
Dermapen 4.0 microneedling is ideal for those looking to improve the appearance of:
It’s suitable for both younger and more mature clients. The treatment should be preceded by a specialist consultation, during which a cosmetologist will assess your skin and develop a personalized plan.
STEP I: Makeup Removal
STEP II: Application of Numbing Cream (30 minutes)
STEP III: Disinfection
STEP IV: Microneedle Mesotherapy
STEP V: Protective Cream with SPF 50
The Dermapen 4.0 treatment significantly smooths wrinkles, minimizes the appearance of pores, and reduces the visibility of scars and stretch marks. For individuals experiencing hair loss, it helps to slow down or stop the shedding process.
Contraindications for microneedle mesotherapy with Dermapen 4.0 include skin conditions of allergic, viral, bacterial, or fungal origin. The treatment is also not suitable for pregnant or breastfeeding women, individuals with cancer, uncontrolled diabetes, a tendency to develop keloid scars, or those experiencing general malaise due to viral infections.
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Results will be visible after just one treatment. The skin will become firmer, more hydrated, and radiant, with imperfections noticeably smoothed out.
Absolutely! Microneedle mesotherapy can be combined with chemical peels, provided it is first discussed during a consultation with a cosmetologist.
The number and intensity of treatments depend on the condition of the skin. In most cases, a series of 3 sessions spaced 2 to 4 weeks apart is sufficient.
Each of the mentioned types of mesotherapy is a completely separate procedure. Needle-free mesotherapy does not involve skin puncture and uses electroporation to deliver active ingredients. Needle mesotherapy is performed using syringes and needles with a thickness of up to 0.6 mm. Microneedle mesotherapy is carried out using a special device equipped with pulsating needles, typically 0.2–0.3 mm thick.
The needles penetrate the skin at a depth of 0.5 mm to 2.5 mm. Most patients describe the pain level as minimal thanks to the application of a numbing cream beforehand, although sensitivity may vary from person to person.