Microneedle Mesotherapy – how to professionally hydrate your facial skin

The secret behind the effectiveness of microneedle mesotherapy lies in the fact that it delivers active ingredients directly beneath the skin, bypassing the outer layers of the epidermis. Using a syringe and ultra-fine needles, substances such as hyaluronic acid, vitamins, amino acids, microelements, or customized nutrient cocktails are injected into the skin. Microneedle mesotherapy can be used on various areas of the body — including the abdomen, thighs, buttocks, or scalp — but it is most commonly performed on the face, neck, and décolletage. The desired results may differ depending on the treatment area, but for facial skin, the goals typically include deep hydration, nourishment, firming, brightening, and reducing fine lines. When focused on restoring hydration to the facial skin, mesotherapy uses specially formulated blends, particularly rich in hyaluronic acid — a key ingredient found in nearly every skincare product for dry or dehydrated skin. However, when injected directly into the deeper layers of the skin in the right concentration, hyaluronic acid becomes significantly more effective than when applied topically in creams or serums. Its primary function in this treatment is its exceptional ability to attract and retain moisture within the dermis, making it a powerful tool for restoring optimal skin hydration and elasticity.

Patients preparing for microneedle mesotherapy often worry about the discomfort caused by the needle punctures and the injection of the active formula. However, it’s important to know that after an initial consultation to rule out any contraindications, the first step of the procedure involves applying a numbing cream, which significantly reduces discomfort during the treatment. Next, the specialist prepares a customized cocktail tailored to the skin’s needs. For hydration, this typically includes regenerating ingredients, hyaluronic acid, and vitamin C. The blend is injected just under the skin using a syringe with an extremely fine needle. Injections are made every 5–10 mm, at a depth of about 2–3 mm, depending on the skin’s condition. The entire procedure usually takes about 90 minutes, depending on the treated area and individual recommendations. Noticeable results from the active ingredients can often be seen within a week. Since mild redness or bruising may appear, it’s best to allow 2 to 3 days for recovery. A full treatment plan typically involves a series of sessions, as advised by the specialist. The result is deeply hydrated, firmer, and more radiant skin, with reduced signs of fatigue and aging.

Thanks to the ability to individually tailor the active ingredients used during injections, microneedle mesotherapy is recommended for a variety of aesthetic skin concerns. Most commonly, it is performed on patients with dry, tight, or dehydrated skin, as well as those showing visible signs of fatigue and moisture loss, or simply looking to prevent these issues. The treatment is suitable for both young and mature skin — the difference lies in the specific composition of active substances chosen for each case. The selection of ingredients is determined by a cosmetologist or aesthetic medicine doctor, who first evaluates the condition and needs of the patient’s skin during a consultation.

During this initial consultation, the specialist also identifies any contraindications to ensure the treatment can be safely performed. The most common contraindications include:

• pregnancy and breastfeeding,
• active cancer,
• use of anticoagulant medications,
• skin infections or inflammatory conditions,
• allergy to any ingredient in the preparation.

The final decision regarding eligibility is always made by the specialist, who carefully assesses the risk of any potential side effects related to the subcutaneous injection of active substances.

At the Anti-Aging Clinic, a wide range of microneedle mesotherapy treatments are available, each tailored to different skin types and concerns — or used preventively to maintain healthy, radiant skin. Despite the different indications, every treatment is focused on deep hydration and nourishment of the injected area. In addition to fully personalized mesotherapy, the clinic offers the following specialized options:

• Biorevitalizing and Hydrating Microneedle Mesotherapy – This treatment delivers a powerful cocktail of 44 active ingredients directly into the skin. The NCTC complex found in the ampoule includes hyaluronic acid, 11 vitamins, 23 amino acids, 6 minerals, and 3 coenzymes. The hyaluronic acid used has an endogenous concentration, meaning it mimics the natural level found in youthful skin. The procedure speeds up skin regeneration, and after just one week, the skin becomes visibly hydrated and firmer.

• Mesopeel Superficial Microneedle Mesotherapy – An original three-step treatment developed by the Anti-Aging Clinic. It begins with the application of a glycolic acid peel enriched with vitamins E and F, followed by mesotherapy using a device to deliver an ampoule with hyaluronic acid and vitamins, and ends with a regenerating mask. This lighter form of traditional microneedling may cause slight redness for a few hours after the session due to shallow skin punctures. However, the effect is nearly immediate — patients leave the clinic with smoother, nourished, and deeply hydrated skin.

• Microneedle Mesotherapy for Mature Skin – Maintaining proper skin hydration is key to delaying signs of aging, but eventually, every skin will need more targeted care. This treatment is designed specifically for mature skin and focuses on plumping, firming, smoothing, and hydrating. The formula used contains a cocktail of carefully selected vitamins combined with non-crosslinked hyaluronic acid. This powerful blend includes 59 active ingredients that support skin restructuring and strengthening, helping to restore a youthful, refreshed appearance.

Hydrating microneedle mesotherapy can be performed regardless of the season, but late summer and early autumn are especially recommended times to focus on restoring proper skin hydration. Why? After weeks of exposure to intense sun, wind, air conditioning, and a lack of proper skin protection, the skin often shows signs of dehydration and dryness. It’s also important to remember that the coming months can be equally challenging for the skin. Indoor heating, cold air, and strong winds can all affect the skin’s moisture balance, leading to tightness and redness if not properly cared for. Professional hydration through microneedle mesotherapy helps prevent these problems and acts as an effective preventive treatment, keeping your skin in excellent condition year-round.